Crossover Trial Sample Size Calculator. This calculator is designed for binary outcomes in parallel group non-inferiority trials. Calculating sample size one would use a standard formula for time to failure and select as the candidate sample size the larger of the sizes required to achieve the desired power for example 80 percentfor each of the two endpoints.
A binary outcome has two categories such as deadalive hospitalisation - yesno therapeutic successfailure and so on. Contingency table involving small numbers and the Χ 2 test. Reduction of sample size is consistent with the principle in medical research to use resources wisely.
Calculate sample size for cluster randomised trials includes cluster cross-over and stepped wedge Resources.
Reduction of sample size is consistent with the principle in medical research to use resources wisely. The mean outcome is compared between the experimental and standard treatment groups. I go to GPower I select repeated measures within factors. References and Additional Reading Rosner B.
